Tiger Tank 59 � A-Gun MP009
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"Tiger Tank 59" is a top-down shooting gameIn this game, Players need to control their tanks,through the enemy lines, break the enemy base,or defeat the enemy tanksFeatureThis DLC contains the Map No.61-65Gameplay Tiger Tank 59 Ⅰ A-Gun MP009:Maternal serum metalloproteinase inhibitor 2 concentrations in normal pregnancies and pregnancies complicated by fetal neural tube defects.
To estimate the potential diagnostic value of a maternal serum metalloproteinase inhibitor 2 (TIMP2) in cases of suspected fetal neural tube defects (NTDs), we measured serum TIMP2 concentrations in 157 pregnant women with fetal NTDs and in 58 controls, recruited between 22 weeks and 36 weeks' gestation. TIMP2 concentrations were measured in all samples by specific sandwich ELISA. TIMP2 levels in the NTDs group were compared to those in controls, and to serum unconjugated estriol, alpha-fetoprotein and human chorionic gonadotropin. TIMP2 levels were not associated with the presence of fetal NTDs or the anatomic subtype. We found no significant difference between the NTDs group and controls in mean TIMP2 levels. However, the mean TIMP2 value in pregnancies with the closed (73 pg/ml, SD 20 pg/ml) was significantly lower than in pregnancies with the open (179 pg/ml, SD 52 pg/ml) (p = 0.008). When the open and closed groups were combined, the mean TIMP2 level was significantly higher in the NTD group than in the control group (p = 0.001). Furthermore, TIMP2 concentrations in the NTD group were significantly lower than in the controls in all subgroups, including the patients in whom screening for fetal NTDs had not been undertaken. Serum TIMP2 concentration is lower in fetuses with open NTDs than in controls. Low serum TIMP2 levels in pregnancies with fetal NTDs may reflect impaired chorioallantoic fusion, possibly due to abnormal expression or function of TIMP2.Q:
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