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In the last two decades, medical imaging has evolved into a powerful tool used by radiologists to aid in the evaluation of diseases. A recently developing field in the medical arena is that of functional brain imaging and treatment. This paper will describe the current state of the art in this area, and will focus on the NeuroQuant(TM) system. By using quantitative imaging, the patient's brain is imaged during application of a stimulating stimulus. From the images, the system can produce a quantitative image detailing the quantitative blood flow, blood volume, or blood oxygen level in the brain. It is hoped that this technology will allow physicians to develop new diagnostic techniques and treat brain diseases before they become permanent.
Introduction
In the previous decade, the use of functional brain imaging to investigate disorders of the human brain was increasing. However, the technology used was qualitatively based and lacked quantification. This hinders the recognition of problems, since such an analysis lacks sensitivity and specificity. This paper describes one of the latest developments in the area of this technology and more particularly in the NeuroQuant(TM) system.
For the first time, quantitative imaging is being done as a part of the diagnosis. Before this, diagnostic studies were qualitative and patients were treated prior to further study of the brain. The results of these tests were subject to human error, time consuming analysis, and were not sufficient to determine the degree of disease. Qualitative brain mapping uses a number of techniques to image the brain including Single Photon Emission Computerized Tomography (SPECT), Functional Trans-Cranial Doppler Ultrasonography (fTCD), Single Photon Emission Computerized Tomography (SPECT), Positron Emission Tomography (PET) etc. These imaging studies are qualitative rather than quantitative and indicate changes in the degree of function/dysfunction of the brain, but do not indicate how much the change in function/dysfunction is.
For example, one could image the brain in a patient who has a tumor and find decreased activity in a specific area. However, one cannot simply assume that the degree of function in that particular area is the same as a patient without the tumor, nor can one assume that the activity is the same degree of function. Thus, quantitative imaging has the potential to become an important tool in the diagnosis and treatment of the human brain.
By using quantitative functional imaging, it is possible to more easily diagnose and treat disease within the brain and determine when treatment is necessary. For
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Suitable for all common operating systems: Windows, Linux, UNIX (Solaris).
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Solaris 7/Solaris 8 (SPARC)
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Windows 2000/XP/2003.
Windows 2000/XP/2003
Solaris 7/Solaris 8 (SPARC)
Apple Macintosh OS X 10.4
Java 2 Runtime Environment
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