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The aim of the study was to compare the efficacy of two sclerosants in the treatment of oesophageal varices. Forty-three patients with oesophageal varices who did not respond to interventional therapy with injection of hyaluronic acid (HA), then received an injection of polidocanol 1% (POL), while 40 patients previously treated with HA received 2 ml of POL. The patients were evaluated by haemoglobin (Hb) measurement, ultrasound (US) and endoscopy before and 1, 2 and 4 weeks after treatment. A significant improvement in the Hb level and the haematological and endoscopic parameters was noted in both groups. There were no significant differences between the groups with regard to the efficacy of treatment. Polidocanol is a safe and effective sclerosant for the treatment of oesophageal varices in patients who have previously undergone the treatment with HA.
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