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Preface xiiAcknowledgments xvPART I INTRODUCTION1 Life, Cell and Thermodynamics 11 The Origin of Life 22 Cellular Architecture 53 Thermodynamics 112 Physical and Chemical Properties of Water 231 Physical Properties of Water 242 Chemical Properties of Water 31PART I I BIOMOLECULES3 Overview of DNA Structure, Function, and Engineering 421 Nucleotides 432 Introduction to Nucleic Acid Structure 463 Overview of Nucleic Acid Function 504 Nucleic Acid Sequencing 535 Manipulating DNA 664 Amino Acids 801 Amino Acid Structure 812 Stereochemistry 883 Amino Acid Derivatives 915 Polypeptide Analysis, Sequencing and Evolution 971 Polypeptide Diversity 982 Protein Purifi cation and Analysis 993 Protein Sequencing 1104 Protein Evolution 1196 Proteins: Structure and Folding 1311 Secondary Structure 1322 Tertiary Structure 1453 Quaternary Structure and Symmetry 1584 Protein Stability 1605 Protein Folding 1657 Physiological Activities of Proteins 1801 Oxygen Binding to Myoglobin and Hemoglobin 1812 Muscle Contraction 2003 Antibodies 2128 Saccharide Chemistry 2211 Monosaccharides 2222 Polysaccharides 2283 Glycoproteins 2349 Lipids, Bilayer and Membranes 2451 Lipid Classifi cation 2462 Lipid Bilayers 2593 Membrane Proteins 2624 Membrane Structure and Assembly 26910 Passive and Active Transport 2931 Thermodynamics of Transport 2942 Passive-Mediated Transport 2953 Active Transport 309PART I I I ENZYMES11 Mechanisms of Enzyme Action 3221 General Properties of Enzymes 3232 Activation Energy and the Reaction Coordinate 3273 Catalytic Mechanisms 3304 Lysozyme 3395 Serine Proteases 34512 Properties of Enzymes 3611 Reaction Kinetics 3622 Enzyme Inhibition 3743 Control of Enzyme Activity 3824 Drug Design 39113 Hormones and Signal Transduction 4021 Hormones 4032 Receptor Tyrosine Kinases 4083 Heterotrimeric G Proteins 4234 The Phosphoinositide Pathway 432PART IV METABOLISM14 Bioenergetics 4421 Overview of Metabolism 4432 High-Energy Compounds 4523 Oxidation–Reduction Reactions 4624 Experimental Approaches to the Study of Metabolism 46815 Glycolysis and the Pentose Phosphate Pathway 4781 Overview of Glycolysis 4792 The Reactions of Glycolysis 4813 Fermentation: The Anaerobic Fate of Pyruvate 4974 Regulation of Glycolysis 5025 Metabolism of Hexoses Other than Glucose 5086 The Pentose Phosphate Pathway 51216 Additional Pathways in Carbohydrate Metabolism 5231 Glycogen Breakdown 5242 Glycogen Synthesis 5323 Control of Glycogen Metabolism 5364 Gluconeogenesis 5445 Other Carbohydrate Biosynthetic Pathways 55117 The Citric Acid Cycle 5581 Overview of the Citric Acid Cycle 5592 Synthesis of Acetyl-Coenzyme A 5623 Enzymes of the Citric Acid Cycle 5684 Regulation of the Citric Acid Cycle 5755 Reactions Related to the Citric Acid Cycle 57918 Mitochondrial ATP Synthesis 5881 The Mitochondrion 5892 Electron Transport 5933 Oxidative Phosphorylation 6094 Control of Oxidative Metabolism 62019 Photosynthesis 6301 Chloroplasts 6312 The Light Reactions 6353 The Dark Reactions 65120 Synthesis and Degradation of lipids 6641 Lipid Digestion, Absorption, and Transport 6642 Fatty Acid Oxidation 6713 Ketone Bodies 6854 Fatty Acid Biosynthesis 6865 Regulation of Fatty Acid Metabolism 6976 Synthesis of Other Lipids 7007 Cholesterol Metabolism 70621 Synthesis and Degradation of Amino Acids 7181 Protein Degradation 7192 Amino Acid Deamination 7243 The Urea Cycle 7284 Breakdown of Amino Acids 7335 Amino Acid Biosynthesis 7466 Other Products of Amino Acid Metabolism 7587 Nitrogen Fixation 76422 Regulation of Fuel Metabolism 7731 Organ Specialization 7742 Hormonal Control of Fuel Metabolism 7813 Metabolic Homeostasis: The Regulation of Energy Metabolism, Appetite, and Body Weight 7864 Disturbances in Fuel Metabolism 790PART V GENE EXPRESSION AND REPLICATION23 Nucleotide Synthesis and Degradation 8021 Synthesis of Purine Ribonucleotides 8022 Synthesis of Pyrimidine Ribonucleotides 8093 Formation of Deoxyribonucleotides 8124 Nucleotide Degradation 82024 DNA structure and Interactions with Proteins 8311 The DNA Helix 8322 Forces Stabilizing Nucleic Acid Structures 8483 Fractionation of Nucleic Acids 8564 DNA–Protein Interactions 8595 Eukaryotic Chromosome Structure 86825 DNA Synthesis and Repair 8791 Overview of DNA Replication 8802 Prokaryotic DNA Replication 8823 Eukaryotic DNA Replication 8984 DNA Damage 9045 DNA Repair 9096 Recombination 91626 RNA Metabolism 9381 Prokaryotic RNA Transcription 9392 Transcription in Eukaryotes 9483 Posttranscriptional Processing 96127 The Genetic Code and Translation 9821 The Genetic Code 9832 Transfer RNA and Its Aminoacylation 9883 Ribosomes 9964 Translation 10045 Posttranslational Processing 102428 Gene Expression in Prokaryotes and Eukaryotes 10331 Genome Organization 10342 Regulation of Prokaryotic Gene Expression 10433 Regulation of Eukaryotic Gene Expression 10524 The Cell Cycle, Cancer, Apoptosis, and Development 1080Glossary G-1 Index I-1SOLUTIONS to Odd-Numbered Problems SP-1pls if anyone has it pls pls send Fundamentals of Biochemistry 5th edition Voet, Voet, Pratt
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