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By ExtremeTech Staff on September 21, 2001 at 9:41 am This site may earn affiliate commissions from the links on this page. Terms of use.The Human-Computer Interaction Lab at the University of Maryland monitors the development and implementation of user interfaces. HCLI partners with other groups to sponsor research projects, which fall into five categories: Visualization (the on-screen representation of application options), Education (the role of technology—instruction, access to the Web, interactive systems—in education), Digital Libraries (digital-library design based on usability research), Design Process (determining the successful components of a design process), and Physical Interfaces (ways to enter data other than a keyboard and mouse, such as tablets). The site lists projects under each of these categories, and you can access the research papers that result from the projects. The projects are many and varied, so the site acts as a valuable resource on human-computer interaction. This site may earn affiliate commissions from the links on this page. Terms of use. Explore resources and articles related to the human bodys shape and form, including organs, skeleton, muscles, blood vessels, and more. Principal Investigator: Marlene Williams, M.D. Department: Medicine Dr. Williams research focuses on platelet physiology particularly as it relates to acute coronary syndromes and depression. Her laboratory specifically examines platelet aggregation, flow cytometric analysis to measure platelet activation, platelet luminescence as a measure of the platelet release reaction, many Elisa preparations in order to measure platelet function, platelet genotyping to determine the presence of certain platelet polymorphisms, and various other assays to distinguish mechanisms of platelet dysfunction. The goal for her cardiovascular platelet laboratory is to identify the etiology of platelet dysfunction in many disease states and apply methods that may improve this dysfunction that can eventually be translated to therapies for patients with cardiovascular disease. Scientific techniques performed in the lab include: flow cytometric analysis, platelet microparticle identification, and protein immunoprecipitation among other techniques. Research Areas: platelets, Platelet drug response, Platelet Flow cytometric analysis, Platelet Aggregation Find a Research Lab Edit lab profile Swallowing disorders (dysphagia) can be a devastating consequence after a stroke and other neurological disorders, trauma or surgery. Our research team aims to reduce the burden of swallowing disorders by learning more about normal and impaired swallowing. We use this knowledge to inform our diagnosis and treatment protocols in patients with dysphagia. Our Team Postdoctoral Research FellowDr. Mulheren completed her doctorate under Dr. Christy Ludlow at James Madison University. Her research focuses on the neurophysiology and instrumental evaluation of swallowing. She is a licensed speech-language pathologist. She has taught graduate-level courses for speech-language pathologists and has presented her research nationally and internationally. Study Information: For many of the 5.4 million stroke survivors in the United States, communication and swallowing problems limit social interactions. This research will look at the areas of the brain that are associated with swallowing and communication difficulties if affected by stroke.Research goal No. 1: identify the neuro-anatomical locations associated with the coexistence of specific types of speech, language andor swallowing disorders, as opposed to those that are only relevant to one.Research goal No. 2: determine the role of acute stroke severity and volume in the development of dysfunction.Swallow Function in Older Adults: Characterizing Changes in Swallowing PhysiologyStudy Information: As we grow older, aspects of the swallowing mechanism change. Our lab studies the aging swallow by analyzing videofluoroscopic swallow studies (VFSS) for both young and elderly patients. Understanding changes between the VFSS results of young and elderly patients is important for preventing unnecessary diet recommendations and overdiagnosis.Research goal No. 1: determine how a standardized assessment reflects the functional aging swallow.Research goal No. 2: make clinicians more aware of the difference between young and elderly swallowing to prevent unnecessary treatments.Upper Esophageal Sphincter (UES) Physiology: develop better understanding using 320-row area detector computed tomography (in collaboration with the Fujita Health University)Research goal No. 1: determine the effect of ischemic stroke on the timing of UES opening relative to swallow initiation.Research goal No. 2: characterize the dynamic relationship between laryngeal vestibule closure (a protective mechanism of the airway during swallowing) and UES dysfunction after stroke.Upcoming projectsOur team also conducts research in the following area:Swallowing Function and Palatability of Barium PreparationsStudy Information: People with different genetic taste backgrounds may swallow differently, which plays a role in how pleasant or unpleasant a food or liquid tastes.Research goal No. 1: determine how people with different genetic taste backgrounds swallow.Research goal No. 2: determine how people with different genetic backgrounds rate pleasantness of food and liquid with and without barium.FundingOur funding comes from the National Institute on Deafness and Other Communication Disorders (NIDCD) under the National Institute of Health (NIH).Featured PublicationsSupratentorial Regions of Acute Ischemia Associated With Clinically Important Swallowing Disorders. Authors: Marlis Gonzalez-Fernandez, Jonathan T. Kleinman, Paul K.S. Ky, Jeffrey B. Palmer, Argye E. HillisDysphagia in Stroke and Neurologic Disease. Authors: Marlis Gonzalez-Fernandez, Stephanie K. DanielsContactSwallowing Investigation in Physiology98 S. BroadwaySuite 403Baltimore, MD 21287OrPhysical Medicine & Rehabilitation600 N. Wolfe St. Phipps 174Baltimore, MD 21287Phone: 410-502-2438Office fax:

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