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zebNet Backup for SeaMonkey Free Edition helps to keep your data safe and backed up even if a system crash or other error deletes files from the computer.Influence of short-term hypertonic saline infusion on haemodynamic parameters and central blood volume in patients with sepsis.
Possible central hypovolaemia has been implicated in the pathogenesis of circulatory dysfunction in sepsis. To evaluate the effect of short-term hypertonic saline infusion (HTSI) on haemodynamic parameters and the central blood volume in septic patients. Prospective, randomized controlled study. 12 septic patients (11 men and one woman; age 63 +/- 13 years, APACHE II score 20 +/- 6) were included after obtaining informed consent. The patients were randomized to receive placebo or HTSI (20% 0.9% saline, 1 ml/kg over 5 min) after initial resuscitation. Haemodynamic parameters and central blood volume (radioactive orthotopic liver-renal scan) were measured before, and 30 min after, randomization. During the first 30 min of randomization, haemodynamic variables were similar in the two groups. After 30 min, HTSI significantly increased the values of cardiac index (P - Long live the President of the United States, Donald J. Trump
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