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Download: LinkA systematic review of the association of physical activity and health-related quality of life in patients with a congenital heart disease.
People with a congenital heart disease (CHD) are at increased risk of developing physical inactivity and low health-related quality of life (HRQOL). However, a systematic review of the association between physical activity and HRQOL in this population is lacking. The objective of this systematic review was to evaluate the association between physical activity and HRQOL in adults with CHD. We searched MEDLINE, PsycINFO, Embase, and Cochrane Library for peer-reviewed papers published between January 1997 and July 2016. All studies reporting physical activity and HRQOL in a CHD population were included. Physical activity was measured using self-report, objective, or combined methods. HRQOL was measured using validated questionnaires or visual analogue scales. Nine studies met the inclusion criteria. Two studies were performed in adults with CHD post heart transplantation. Two studies were performed in adults with CHD post valvular surgery. Four studies were performed in adults with CHD at any stage of their disease. Seven studies used the 6-Minute Walk Test (6MWT), one used the maximal treadmill test (MTT) and one used the Six-Minute Walk Questionnaire (SMWQ). Two studies included the Pediatric Quality of Life Inventory (PedsQL) as a measure of HRQOL. Total physical activity was positively associated with the Physical Functioning (PF) and the Mental Health (MH) subscale of the PedsQL (95% confidence interval (CI) 0.20 to 0.42, and 95% CI 0.01 to 0.20, respectively) and the 6MWT (95% CI 0.12 to 0.44) in adult patients with CHD. The only study examining the association between moderate-to-vigorous physical activity
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